Sheikh Mohammed has been responsible for the creation and rapid growth of a number of businesses and key economic assets to Dubai, with a number held by two companies under his ownership, Dubai World and Dubai Holding.

Dubai World was launched on 2 July 2006, as a holding company consolidating a number of assets including logistics company DP World, property developerNakheel Properties and investment company Istithmar World. With more than 50,000 employees in over 100 cities around the globe, the group has real estate, logistics and other business investments in the United States, the United Kingdom and South Africa.

Dubai Holding develops and manages hospitality, business parks, real estate and telecommunications through four operating units: Jumeirah Group, TECOM Investments, Dubai Properties Group and Emirates International Telecommunications. The company's investment group operating units include Dubai Group andDubai International Capital.